Learn about the different types of techniques used to sequence DNA. We'll go over everything from maxam gilbert sequencing, sanger ddNTP sequencing to shotgun sequencing.
Get a gist of what DNA sequencing is, what types of molecules can be sequenced, what breadth of information comes out of DNA sequencers, and the types of sequencing approaches available.
Learn about the very first DNA sequencing technique pioneered by Alan Maxam and Walter Gilbert in 1976.
Learn how Sanger sequencing works, which relies heavily on the chemical properties of dideoxynucleotides (ddNTPs). Also learn the pros and cons of the technique.
Learn how scientists deal with the disadvantage of having short reads by utilizing a method known as primer walking.
Learn how to get around the limitations of pyrosequencing by incorporating all four nucleotides in one run with reversible chain terminators.
Learn the technique they used to sequence genomes that haven't been sequenced before (de novo) with the shotgun sequencing method.